Avoid ALL CAPS sentences. ALL CAPS can be difficult to read and can be read incorrectly by screen reader.
An ALL CAPS word creates a parallel edge at the top and bottom, giving the word a low shape contrast. Text in Non Caps shows multiple adjacent edges at the top and bottom, giving the word a higher shape contrast.
Example of Word Shape Contrast
The more non-parallel edges your text has, the higher the shape contrast. High shape contrast makes words easier for users and easier for screen readers to recognize the word.
Screen Readers also have difficulty translating/reading text in ALL CAPS. The following example is how a screen reader sees and translates an ALL CAPS sentence. The result is no longer readable or understandable.
Example
Text on Screen THIS SENTENCE IS IN ALL CAPS
Screen Reader T. H. I. S. S. E. N. T. E. N. C. E. I. S. I. N. A. L. L. C. A. P. S.